dpp4inhibitormechanism

由KDungan著作·被引用10次—MECHANISMOFACTION·SUGGESTEDAPPROACH·Patientselection·Contraindicationsandprecautions·ChoiceofDPP-4inhibitor·Dosing·- ...,由SVSKKasina著作·2023·被引用48次—Thesedrugsactthroughincretinhormones,whichareguthormonesresponsibleforglucosehomeostasisafteroralfoodintake.Apartfromantihyperglycemic ...,,DPP-4inhibitorsworkbyblockingtheactionofDPP-4,anenzymewhichdestroysthehormone...

參考資訊如下
Dipeptidyl peptidase 4 (DPP

由 K Dungan 著作 · 被引用 10 次 — MECHANISM OF ACTION · SUGGESTED APPROACH · Patient selection · Contraindications and precautions · Choice of DPP-4 inhibitor · Dosing · - ...

Dipeptidyl Peptidase IV (DPP IV) Inhibitors

由 SVSK Kasina 著作 · 2023 · 被引用 48 次 — These drugs act through incretin hormones, which are gut hormones responsible for glucose homeostasis after oral food intake. Apart from antihyperglycemic ...

Dipeptidyl peptidase-4 inhibitor

DPP

DPP-4 inhibitors work by blocking the action of DPP-4, an enzyme which destroys the hormone incretin. Incretins help the body produce more insulin only when ...

DPP-4 inhibitors for treating T2DM

由 K Saini 著作 · 2023 · 被引用 18 次 — DPP-4 has two mechanisms of action: first as a membrane spanning protein, where it binds and activates adenosine deaminase complexing protein and transfers ...

Mechanism of Action of DPP

由 A Vella 著作 · 2012 · 被引用 84 次 — In practice, DPP-4 inhibitors increase concentrations of both active incretin hormones, GLP-1 and glucose-dependent insulinotropic polypeptide (secreted by the ...

Mechanism of action of inhibitors of dipeptidyl-peptidase

由 NA Thornberry 著作 · 2009 · 被引用 326 次 — Dipeptidyl-peptidase IV (DPP-4) inhibitors inhibit the degradation of the incretins, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic ...

Pharmacology, Physiology, and Mechanisms of Action of ...

由 EE Mulvihill 著作 · 2014 · 被引用 571 次 — Dipeptidyl peptidase-4 (DPP4) is a widely expressed enzyme transducing actions through an anchored transmembrane molecule and a soluble circulating protein.

Pleiotropic Mechanisms for the Glucose

2014年6月14日 — The classical mechanism for DPP-4 inhibitors is that they inhibit DPP-4 activity in peripheral plasma, which prevents the inactivation of the ...